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In vitro assessments demonstrated positive effects on bronchial epithelial barrier repair including increased proliferation and migration although averting apoptosis via dampening of the Bax/Bcl2 ratio [118]
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On the other hand, elevated TBC1D15 expression to increase Rab7 hydrolysis reduced membrane contacts between LE/Lys and mitochondria to confer neuroprotective effects against neuronal injury induced by epileptic seizure [86]
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